ANTI-PYRETIC AND ANTI-INFLAMMATORY ACTIVITY OF AQUEOUS EXTRACT OFSOLANUM XANTHOCARPUM BERRIES IN SUITABLE ANIMAL MODELS

Background: Use of traditional medicines for treating various diseases have become a topic global importance because their safety, less side effects and cost-effectiveness. The present study was undertaken to evaluate the anti-pyretic anti-inflammatory activity aqueous extract Solanum xanthocarpum berries (SXB) in suitable animal models. Methods: Anti-pyretic assessed by dried yeast induced pyrexia rats. Anti-inflammatory evaluated using carrageenan paw oedema Three doses plant (500, 1000 1500 mg/kg) prepared dissolving drugs 2% gum acacia were used. Paracetamol 33 mg/kg aspirin 100 used as standard respectively. Vehicle served control drug. Results: Acute toxicity results demonstrated no mortality animals after 24 hours. significantly decreased rectal temperature rats prevented increase volume oedema. Conclusion: exerts its activity. However, further studies with are required dose dependent also determine active principle responsible exact mechanism both antipyretic